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Bioinformatics is the application of information technology and computer science to the field of molecular biology. The term bioinformatics was coined by Paulien Hogeweg in 1979 for the study of informatic processes in biotic systems. Its primary use since at least the late 1980s has been in genomics and genetics, particularly in those areas of genomics involving large-scale DNA sequencing. Bioinformatics now entails the creation and advancement of databases, algorithms, computational and statistical techniques, and theory to solve formal and practical problems arising from the management and analysis of biological data. Over the past few decades rapid developments in genomic and other molecular research technologies and developments in information technologies have combined to produce a tremendous amount of information related to molecular biology. It is the name given to these mathematical and computing approaches used to glean understanding of biological processes. Common activities in bioinformatics include mapping and analyzing DNA and protein sequences, aligning different DNA and protein sequences to compare them and creating and viewing 3-D models of protein structures.
Additional info
Accuracy
In the fields of engineering, industry and statistics, the accuracy of a measurement system is the degree of closeness of measurements of a quantity to its actual (true) value. The precision of a measurement system, also called reproducibility or repeatability, is the degree to which repeated measurements under unchanged conditions show the same results.[1] Although the two words can be synonymous in colloquial use, they are deliberately contrasted in the context of scientific method.Aerospace
Aerospace comprises the atmosphere of Earth and surrounding space. Typically the term is used to refer to the industry that researches, designs, manufactures, operates, and maintains vehicles moving through air and space. Aerospace is a very diverse field, with a multitude of commercial, industrial and military applications.Aerospace engineering
Aerospace engineering is the branch of engineering behind the design, construction and science of aircraft and spacecraft. It is broken into two major and overlapping branches: aeronautical engineering and astronautical engineering. The former deals with craft that stay within Earth's atmosphere, and the latter deals with craft that operate outside of Earth's atmosphere.Agricultural engineering
Agricultural engineering is the engineering discipline that applies engineering science and technology to agricultural production and processing. Agricultural engineering combines the disciplines of animal biology, plant biology, and mechanical, civil and chemical engineering principles with a knowledge of agricultural principles. It involves a broader scope engineering in all the world then any other engineering discipline. It utilizes the knowledge of engineering for making agricultural machinery. [1]Alpha taxonomy
Alpha taxonomy (or sometimes simply taxonomy) is the science of finding, describing and categorising organisms, thus leading to the recognition of proposed taxonomic groups, or taxa (singular: taxon), which may then be named.Amino acid
Amino acids are molecules containing an amine group, a carboxylic acid group and a side chain that varies between different amino acids. These molecules are particularly important in biochemistry, where this term refers to alpha-amino acids with the general formula H2NCHRCOOH, where R is an organic substituent.[1] In the alpha amino acids, the amino and carboxylate groups are attached to the same carbon atom, which is called the α–carbon. The various alpha amino acids differ in which side chain (R group) is attached to their alpha carbon. These side chains can vary in size from just a hydrogen atom in glycine, to a methyl group in alanine, through to a large heterocyclic group in tryptophan.Ammunition
Ammunition, often informally referred to as ammo, is a generic term derived from the French language la munition which embraced all material used for war (from the Latin munire, to provide), but which in time came to refer specifically to gunpowder and artillery. The collective term for all types of ammunition is munitions. In the widest sense of the word it covers anything that can be used in combat that includes bombs, missiles, warheads, and mines (landmines, naval mines, and anti-personnel mines) – that munitions factories manufacture. The purpose of ammunition is predominantly to project force against a selected target. However, the nature of ammunition use also includes delivery or combat supporting munitions such as pyrotechnic or incendiary compounds. Since the design of the cartridge, the meaning has been transferred to the assembly of a projectile and its propellant in a single package.Anatomy
Anatomy (from the Greek ἀνατομία anatomia, from ἀνατέμνειν ana: separate, apart from, and temnein, to cut up, cut open. Also from the Greek word "anatome"--ana: apart, tome: to cut-->To cut apart.) is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy (zootomy) and plant anatomy (phytotomy). In some of its facets anatomy is closely related to embryology, comparative anatomy and comparative embryology,[1] through common roots in evolution.Applied mathematics
Applied mathematics is a branch of mathematics that concerns itself with the mathematical techniques typically used in the application of mathematical knowledge to other domains.Approximation algorithms
In computer science and operations research, approximation algorithms are algorithms used to find approximate solutions to optimization problems. Approximation algorithms are often associated with NP-hard problems; since it is unlikely that there can ever be efficient polynomial time exact algorithms solving NP-hard problems, one settles for polynomial time sub-optimal solutions. Unlike heuristics, which usually only find reasonably good solutions reasonably fast, one wants provable solution quality and provable run time bounds. Ideally, the approximation is optimal up to a small constant factor (for instance within 5% of the optimal solution). Approximation algorithms are increasingly being used for problems where exact polynomial-time algorithms are known but are too expensive due to the input size.Archaeology
Archaeology (sometimes written archæology) or archeology (from Greek ἀρχαιολογία, archaiologia – ἀρχαῖος, arkhaīos, "ancient"; and -λογία, -logiā, "-logy") is the science and humanity[1] that studies historical human cultures through the recovery, documentation, analysis, and interpretation of material culture and environmental data, including architecture, artifacts, biofacts, and landscapes. Archaeology aims to understand humankind through these humanistic endeavors.[1] In the United States the field is commonly considered to be a subset of anthropology, along with physical anthropology, cultural anthropology, and linguistic anthropology,[2] whilst in British and European universities, archaeology is considered as a separate discipline.Architectural engineering
Architectural engineering, also known as Building engineering, is the application of engineering principles and technology to building design and construction. Definitions of an architectural engineer may refer to:Artificial intelligence
Artificial intelligence (AI) is the intelligence of machines and the branch of computer science that aims to create it. Textbooks define the field as "the study and design of intelligent agents,"[1] where an intelligent agent is a system that perceives its environment and takes actions that maximize its chances of success.[2] John McCarthy, who coined the term in 1956,[3] defines it as "the science and engineering of making intelligent machines."[4]Artificial life
Artificial life (commonly Alife or alife) is a field of study and an associated art form which examine systems related to life, its processes, and its evolution through simulations using computer models, robotics, and biochemistry.[1] There are three main kinds of alife[2], named for their approaches: soft[3], from software; hard[4], from hardware; and wet, from biochemistry. Artificial life imitates traditional biology by trying to recreate biological phenomena.[5] The term "artificial life" is often used to specifically refer to soft alife.[6]Astrobiology
Astrobiology (other terms have been exobiology, exopaleontology, and bioastronomy) is the study of the origin, evolution, distribution, and future of life in the universe. This interdisciplinary field encompasses the search for habitable environments in our Solar System and habitable planets outside our Solar System, the search for evidence of prebiotic chemistry, life on Mars and other bodies in our Solar System, laboratory and field research into the origins and early evolution of life on Earth, and studies of the potential for life to adapt to challenges on Earth and in outer space.[2]Audio engineering
Audio engineering is a part of audio science dealing with the recording and reproduction of sound through mechanical and electronic means. The field draws on many disciplines, including electrical engineering, acoustics, psychoacoustics, and music. Unlike acoustical engineering, audio engineering does not deal with noise control or acoustical design. An audio engineer is closer to the creative and technical aspects of audio rather than formal engineering. An audio engineer must be proficient with different types of recording media, such as analog tape, digital multitrack recorders and workstations, and computer knowledge. With the advent of the digital age, it is becoming more and more important for the audio engineer to be versed in the understanding of software and hardware integration from synchronization to analog to digital transfers.Automotive engineering
Modern automotive engineering is a branch of vehicle engineering, incorporating elements of mechanical, electrical, electronic, software and safety engineering as applied to the design, manufacture and operation of motorcycles, automobiles, buses and trucks and their respective engineering subsystems.BLAST
In bioinformatics, Basic Local Alignment Search Tool, or BLAST, is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of different proteins or the nucleotides of DNA sequences. A BLAST search enables a researcher to compare a query sequence with a library or database of sequences, and identify library sequences that resemble the query sequence above a certain threshold. For example, following the discovery of a previously unknown gene in the mouse, a scientist will typically perform a BLAST search of the human genome to see if humans carry a similar gene; BLAST will identify sequences in the human genome that resemble the mouse gene based on similarity of sequence. The BLAST program was designed by Eugene Myers, Stephen Altschul, Warren Gish, David J. Lipman and Webb Miller at the NIH and was published in J. Mol. Biol. in 1990[1].Bayesian analysis
Bayesian inference is statistical inference in which evidence or observations are used to update or to newly infer the probability that a hypothesis may be true. The name "Bayesian" comes from the frequent use of Bayes' theorem in the inference process. Bayes' theorem was derived from the work of the Reverend Thomas Bayes.[1]Bernd Sturmfels
Bernd Sturmfels (b. March 28, 1962, Kassel, Germany) is a Professor of Mathematics and Computer Science at the University of California, Berkeley. He received his PhD in 1987 from the University of Washington and the Technische Universität Darmstadt. After two postdoctoral years at the Institute for Mathematics and its Applications in Minneapolis, Minnesota, and the Research Institute for Symbolic Computation in Linz, Austria, he taught at Cornell University, before joining UC Berkeley in 1995. His honors include a National Young Investigator Fellowship, an Alfred P. Sloan Fellowship, and a David and Lucile Packard Fellowship.Biochemical engineering
Biochemical engineering is a branch of chemical engineering or biological engineering that mainly deals with the design and construction of unit processes that involve biological organisms or molecules, such as bioreactors. Biochemical engineering is often taught as a supplementary option to chemical engineering or biological engineering due to the similarities in both the background subject curriculum and problem-solving techniques used by both professions. Its applications are used in the food, feed, pharmaceutical, biotechnology, and water treatment industries.