AIDS pandemic

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The Acquired Immune Deficiency Syndrome (AIDS) pandemic is a widespread disease caused by human immunodeficiency virus (HIV).

AIDS: Acquired immune deficiency syndrome
HIV: Human immunodeficiency virus
CD4+: CD4+ T helper cells
CCR5: Chemokine (C-C motif) receptor 5
CDC: Centers for Disease Control and Prevention
WHO: World Health Organization
PCP: Pneumocystis pneumonia
TB: Tuberculosis
MTCT: Mother-to-child transmission
HAART: Highly active antiretroviral therapy
STI/STD: Sexually transmitted infection/disease

A United States HIV/AIDS Memorial Museum, to be located in Newark, New Jersey, USA, was started in December 2004. Its first pilot program, an exhibit of art by HIV-positive artists entitled "Eyes of Mercy", was held from November 11 through December 1, 2006 at Seton Hall University in South Orange, NJ. The second exhibit was held in March 2007 at Red Saw Art Gallery in Newark, NJ. The AIDS Museum also co-organized an exhibit entitled "Edge of Light: Art in the Age of AIDS" at the Paul Robeson Center Gallery at Rutgers Newark, which ran from July 2007 until December 2007. December 2007 has been a busy month for the AIDS Museum. George Mason University in Virginia also hosted a photographic exhibit by artist Kathy Seward Mackay called "Dying in Vein" about AIDS in the hemophilia community. In addition, artist Nicole Margaretten's sculpture "Roasting the Virus: An Eternal Flame dedicated to those affected by HIV/AIDS" as well as a panel of the AIDS Memorial Quilt were displayed at New School University in New York City. Finally, the World Culture Open Gallery (also in New York) was the site of a collaborative project called "Positive Still: Artists Respond to AIDS" featuring, among other artwork, five pieces from the AIDS Museum's permanent collection. The next exhibit "Lifework" will be hosted at Seton Hall Law School in Newark, NJ in January 2008.

Some advocates hold that HIV was introduced to North America by a flight attendant named Gaëtan Dugas, referred to as "Patient Zero". Other advocates argue that there were cases of AIDS much earlier than initially known.AIDS dementia complex (ADC; also known as HIV dementia, HIV encephalopathy, HIV-associated dementia and HIV-associated neurocognitive disorder) is a common neurological disorder associated with HIV infection and AIDS. It is a metabolic encephalopathy induced by HIV infection and fueled by immune activation of brain macrophages and microglia.[1] These cells are actively infected with HIV and secrete neurotoxins of both host and viral origin. The essential features of ADC are disabling cognitive impairment accompanied by motor dysfunction, speech problems and behavioral change. Cognitive impairment is characterised by mental slowness, trouble with memory and poor concentration. Motor symptoms include a loss of fine motor control leading to clumsiness, poor balance and tremors. Behavioral changes may include apathy, lethargy and diminished emotional responses and spontaneity. Histopathologically, it is identified by the infiltration of monocytes and macrophages into the central nervous system (CNS), gliosis, pallor of myelin sheaths, abnormalities of dendritic processes and neuronal loss.[1][2]

AIDS denialism is the view held by a loosely connected group of persons and organizations who deny that the human immunodeficiency virus (H.I.V.) is the cause of acquired-immune-deficiency syndrome (AIDS).[1] Some denialists reject the existence of H.I.V., while others accept that H.I.V. exists but say that it is a harmless passenger virus and not the cause of AIDS. Insofar as denialists acknowledge AIDS as a real disease, they attribute it to some combination of recreational drug use, malnutrition, poor sanitation, and side effects of antiretroviral medication, rather than infection with H.I.V.HIV, the virus that causes AIDS, originated in non-human primates in sub-Saharan Africa and was transferred to humans during the late 19th or early 20th century.The ASSA AIDS models are a series of mathematical models developed to assist the actuarial profession and the Actuarial Society of South Africa in assessing and addressing the impact of the AIDS epidemic in South Africa.

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